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6 Future perspectives Metabolomics is to become an important tool in research related to the investigation of drug-induced hepatotoxicity, allowing researchers to assess the deleterious effects of xenobiotics by identifying changes in metabolite levels that uncover the toxic mechanisms at play, the identification of biomarkers of interest suitable for clinical diagnosis and facilitating the development of predictive models

That single fractionation study is the proof point researchers still cite more than fifty years later as the origin of the entire copper-peptide research field: a compound identified almost by accident in a liver-aging comparison went on to become one of the most studied metallopeptides in dermal and regenerative research

Significant potency improvements were achieved by replacing the 5-fluoro-pyrimidine (blue) with a pyridyl group

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Disposal: Immediately place used syringe/needle in a sharps container without recapping [5]